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Published safety data from clinical trials report no significant adverse effects across all studied doses and durations
In fact, the peptide has actually been shown to prevent severe side effects associated with medications for diabetes and psychiatric conditions, including catalepsy, somatosensory disturbance, and QTc prolongation in the heartwhich can lead to fatal arrythmia [13, 14]
Experiments involving the mGluR2/3 antagonist LY 341495 indicated that these may enhance the average firing rate of DRN serotonin neurons, a result that was abolished by an electrolytic lesion of the mPFC
(5) J Vukojevic, M Milavi, D Perovi, S Ili, et al (2022)
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