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By assessing the electrophysiological properties of AgRP neurons from animals treated with Semaglutide, our work captured the synaptic adaptations in this circuit in response to sustained energy imbalance, particularly a reduction in inhibitory inputs to AgRP cells, suggesting a shift towards net excitation (Fig
Pharmacological progress in metabolic research models: tirzepatide's rising advantage [PMID: 41497097] Laboratory literature summary: Pharmacological progress in metabolic research models: tirzepatide's rising advantage over semaglutide
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