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Some people experience less nausea and cramping with oral semaglutide compared to injections because absorption is slower and more gradual, though both formulations work through the same GLP-1 pathway
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GLP-1R expression has been found in both the atria and ventricles (Pandey et al., 2023)
This imbalance impairs vasodilation, promotes vasoconstriction, and increases vascular permeability, creating a conducive environment for the infiltration of lipoproteins and immune cells into the arterial wall
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