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The companies tried to knock out twelve of the seventeen counts in the master complaint, arguing that statements about their drugs being safe and effective were non-actionable puffery and that design defect theories were federally preempted

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Intriguingly, in the two PCOS models tested, metformin was only marginally effective in improving the metabolic profile, despite the high dose used and its consideration as gold standard for the treatment of insulin resistance in women suffering PCOS

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Findings from preclinical and postmortem studies highlighted that brain insulin signaling is dysregulated in AD mouse and human brains (Griffith et al

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