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Abnormalities in glutamate and GABA metabolic pathwaysincluding glutamatergic synapse, glutathione metabolism, GABAergic synapse, D-amino acid metabolism, arginine biosynthesis, alanine, aspartate, and glutamate metabolismwere observed in the top 20 (Figure 3C)
Therapeutic implications and future directions As previously stated, the integrity of the BBB is compromised during EBI, with multiple underlying pathophysiological mechanisms, including MMP-9 activity, being identified
The following treatments are commonly used to reduce the symptoms of an allergic reaction: Antihistamines Antihistamines can help to treat most minor allergic reactions regardless of the cause