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In addition, the presence of cysteine residues within the GPx4 protein has been suggested to be critical for its catalytic cycle (Mannes et al., 2011)

Usage Note: For laboratory research use only

It can detoxify cellular lipid peroxidation by using the cofactor (GSH) by converting complex toxic lipid hydroperoxides, such as phospholipid hydroperoxides and cholesterol hydroperoxides, into their corresponding nontoxic lipid alcohols

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