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In a further embodiment of the present invention the GLP-1 peptide to be purified is selected from GLP-1 (7-37), GLP-1 (7-36) amide as well as analogues and derivatives thereof, in particular but not limited to human glucagon-like peptide-1, In a further embodiment of the present invention the GLP-1 related impurities to be removed are selected from but not limited to truncated forms, all kinds of extended forms (extra amino acids, various derivatives including esters etc.), deamidated forms, incorrectly folded forms, forms with undesired glycosylation including sialylation

This presents an ideal scenario to test the viability of medication repurposing, the team said

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For testosterone-adjacent compounds, the useful workflow is to identify the pathway first: HPG-axis signaling, GH-axis signaling, sexual-function signaling, tissue-repair signaling, or metabolic signaling