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Together, these findings underscore that LC's variable clinical efficacy arises from interacting factors including patient phenotype, dosing strategy, intervention duration, and endpoint sensitivity

According to NICE guidance, thyroid function should be monitored regularly, particularly when initiating treatment or adjusting doses, to ensure optimal hormone levels and symptom control

However, some people may want to increase or decrease their IGF-1 levels to increase quality of life in older adulthood, to boost muscle mass, to ward off diabetes, or to lower risk of some cancers

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