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Gelam honey also reduces EMT by upregulating E-cadherin and downregulating Twist and the transcription factor Snail in colorectal cancer models ( Similar anti-metastatic effects have been noted for caffeic and gallic acids, which downregulate MMP and VEGF expression in melanoma and breast cancer cells (126)
In conclusion, eryptosis targeting is a promising therapeutic approach in multiple human diseases that should not be neglected
Kahn MA, Weathers DR, Hoffman JG
Clinical trials have tested the effects of GLP-1R agonists in patients with PD, AD, or diabetes-related memory impairment, showing significant improvement in these patients conditions (69)
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