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In the rodent studies, this overgrowth (hyperplasia) eventually led to medullary thyroid tumours

362 In an experimental study in which osteoclast formation and bone resorption were induced in mice through lipopolysaccharide (LPS) administration, researchers discovered that simultaneous treatment with exendin-4 resulted in a significant decrease in the number of osteoclasts, the proportion of bone resorption pits, and the levels of the bone resorption marker CTX compared to injection with LPS alone

However, it is important to exercise caution when injecting in this area

These systems allow for more versatile activation mechanisms Fig