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The International Journal on Drug Policy
Pulsatile versus tonic GH release biology: Studies comparing the downstream biological consequences of pulsatile GH release (produced by short-acting GHRH analogues and GHRPs) versus tonic GH elevation (produced by long-acting GHRH-DAC variants or continuous GH infusion) established that pulsatile GH patterns are more potent drivers of hepatic IGF-1 production and anabolic GH signalling than equivalent total GH doses delivered continuously providing the physiological rationale for preserving pulsatile GH release characteristics in GH secretagogue research designs
Nonetheless, the precise molecular target of GHK-Cu has not been identified
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