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GCL belongs to the class of proteins that are sensitive to oxidative stress, and its expression is mainly under the regulation of the Nuclear factor (erythroid-derived 2)-like 2 (NFE2L2), a transcription factor that regulates a wide array of antioxidant responsive element-driven genes in various cell types ( the novo GSH biosynthesis is glutathione synthase (GS)
The release of major basic protein and cytokines IL-5, IL-3, and GM-CSF (granulocytemacrophage colony-stimulating factor) from both mast cells and eosinophils activate basophils
A novel GIP analogue, ZP4165, enhances glucagon-like peptide-1-induced body weight loss and improves glycaemic control in rodents
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