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FIGURE 3 Next, we tested the efficacy of dexamethasone against age-related tendinopathy
AT1R expression in mesangial cells and podocytes, induced by high glucose levels, promotes intracellular expression of profibrotic and pro-inflammatory mediators, such as transforming-growth factor beta (TGF- ), vascular endothelial growth factor (VGEF), and interleukin-6 (IL-6) leading to hyperplasia and hypertrophy, mainly of the proximal tubule, together with extracellular matrix production (34)
The study in JAMA is in opposition to another recent analysis which showed a decrease, says obesity expert and lipid specialist Dr
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