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The review further highlights emergent research on "next-generation" therapies with weight-loss efficacy of up to about 24% in clinical trials, approaching weight-loss magnitudes reported in some surgical interventions
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Participants who reported increased cravings had the shortest median duration (approximately 5 months)
Either protocol may be administered twice annually for longevity and anti-aging purposes, and are respectively known as the Russian Protocol and the Ukrainian Protocol [2]
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