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This triple mechanism distinguishes it from dual agonists such as tirzepatide and single agonists such as semaglutide
Randomisation was 21:3:3:7 to cagrilintidesemaglutide 2.4/2.4 mg (n=2108), semaglutide 2.4 mg alone (n=302), cagrilintide 2.4 mg alone (n=302), or placebo (n=705), all with lifestyle intervention [7]
286,287 PNS-resident macrophages surveil the endoneurial space under normal conditions
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