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Algunos pacientes reportan que la administracin nocturna hace que las nuseas ocurran durante el sueo, mientras que la administracin matutina permite implementar estrategias de manejo como comer pequeas cantidades de alimentos blandos o tomar medicamentos antiemticos si estn prescritos
in 1976 [3]
Anna Mapp, a chemist at the University of Michigan and president of the American Peptide Society, reviewed his work and put it bluntly: "There was no demonstration that I could tell that it was a single pure isolated substance" [17][18][19]
Taking them together could potentially intensify these adverse effects, making treatment less tolerable and affecting adherence
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