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In a subanalysis of SURPASS-3, tirzepatide 10 and 15 mg resulted also in a relative reduction in liver fat content by 4047% compared to 11% with insulin glargine at 52 weeks [44]

Written informed consent from the patients/participants or patients/participants' legal guardian/next of kin was not required to participate in this study in accordance with the national legislation and the institutional requirements

Creatine may be appropriate for teen athletes (16+) who participate in serious, competitive, and supervised training, with healthcare provider guidance, under adult supervision

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