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In the stage of cancer progression, administration of high doses of vitamin C, especially in combination with redox-active metals (copper, iron) may increase the cellular prooxidant state triggering cytotoxicity of cancer cells (Pawlowska et al
13), were investigated (Table 2 and Fig
not trial-validated Endpoint Wrinkle depth Topical timeline 8-12 weeks Injectable framing Anecdotal Endpoint Hair shedding or thickness Topical timeline 12+ weeks Injectable framing Anecdotal
Slices were then transferred to wells filled with 600 L of ACSF ( + 100 mM KCl) with DPP4 inhibitors (24 L/600 L) and Aprotinin (9 L/600 L) and incubated for 20 min at 34 C (monitoring of bubbling, keeping slices in motion using a pipette)
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