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GHK-Cu adds another layer of concern because FDA has specifically discussed immunogenicity risk for injectable GHK-Cu related to potential aggregation and peptide-related impurities
They may notice no difference between semaglutide alone and semaglutide with B12, because there was no deficiency to correct
Reported side effects Nausea (dose-dependent, more common at higher doses) Facial flushing and increased skin warmth Reduced appetite and mild fatigue Spontaneous erections or increased libido in men Injection site reactions (redness, mild stinging) Changes in existing moles Transient increases in heart rate and blood pressure Storage Lyophilised (unmixed) Freeze at -20 C (-4 F) or below, in dry, dark conditions
between 2021 and 2023, for example, GLP-1 RA prescriptions shot up by approximately 60%, the two most common brands being Ozempic and Wegovy
