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Hormonal fluctuations can make women more susceptible to shifts in fluid balance, particularly related to their menstrual cycle

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Second, the lack of granular data on GLP-1RA dosing protocols, severity of IBS or obesity, coexisting central sensitization syndromes and the observational nature of the study limit our ability to infer causality

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Weight regain occurs with both medications after discontinuation, but the pattern differs

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