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PMID 9847106
GLP-1 receptor agonists are recommended by NICE when BMI is 35 kg/m (or lower in people of Black African, African-Caribbean, or South Asian family origin) or for whom weight loss would benefit obesity-related comorbidities
Drawing single-use aliquots immediately after reconstitution and holding them frozen, instead of repeatedly re-entering one refrigerated stock, is what preserves a 30mg vial across an extended protocol
The oral bioavailability of the pill may not be the same as with injectables, but the overall clinical efficacy indicates that it can reach sufficient systemic exposure to meet the clinical endpoint
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