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Its efficacy and convenient dosing have driven a marked increase in GLP-1 RA prescriptions, especially from 2020 to 2024, among patients with obesity or diabetes
In a small open-label trial of exenatide in people with clozapine-associated obesity (BMI 3045 kg/m 2 ), those on exenatide had about 10 pounds more weight loss than placebo at 24 weeks (Siskind D et al, J Psychiatr Res 2020;124:912)
Advancing new therapies requires not only innovative science, but also translational research approaches that better reflect the complexity of disease biology
Questions to Ask Your Provider About Monitoring If youre curious about monitoring certain biomarkers while on a GLP-1, talk to your doctor beforehand about what to expect and what information you want to know
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