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These hepatoprotective and anti-inflammatory drugs can inhibit liver inflammation, detoxify, regulate energy metabolism, remove reactive oxygen species and free radicals, improve the stability of liver cell membrane, immune regulation, integrity and fluidity, and ultimately achieve the purpose of reducing liver damage, reducing intrahepatic cholestasis, and promoting liver cell repair and regeneration (Sun et al., 2024) have also found that Hydronidone is able to induce apoptosis in activated HSC through the mitochondrial apoptotic pathway
Zhai C, Wang D
Borthakur G, Ofran Y, Nagler A, Rowe J, Foran J, Uy GL, DiPersio JF, Altman JK, Frankfurt O, Tallman MS, Peled A, Pereg Y, Vainstein A, Aharon A, AlRawi A, McQueen T, Pemmaraju N, Bueso-Ramos C, Cortes JE, Andreeff M
2022;219:e20211498
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