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Most people see additional weight loss resume within 4-8 weeks of switching
Excellent tolerance with minimal side effects doesn't justify accelerating the escalation schedule
Nutrients 10(10):1550 Liu P et al (2024) Linarine inhibits inflammatory responses in dry eye disease mice by modulating purinergic receptors
Ketamine and psilocybin each produce a brief acute experience but set off a wave of synaptic growth afterward, ketamine through glutamate release and mTOR-dependent synapse formation and psilocybin through rapid, lasting growth of dendritic spines in the frontal cortex, both via BDNF signaling, which is why a single session can shift symptoms for weeks
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