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In contrast, when placed under metabolic stress with increased demand on the -cell (induced by high fat feeding and a low dose of the -cell toxin, streptozotocin), glucose tolerance did become impaired, supporting the view that paracrine GLP-1 may be required to maintain glucose homeostasis during adaptation to metabolic stress (114)
But were pretty successful when we use the nebulizing to go a little deeper
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A randomized phase 1 safety, pharmacokinetic and pharmacodynamic study of the novel myostatin inhibitor apitegromab (SRK-015): a potential treatment for spinal muscular atrophy
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