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Mitochondria morphological changes are associated with dysfunction and altered energy metabolism, whereby adenosine triphosphate (ATP) production is insufficient to maintain the Na+/K+-ATPase neuronal activity, which leads to massive calcium (Ca +2 ) influx followed by glutamate toxicity [24]
Circadian gene expression The circadian clock is not just about melatonin levels
The four-week intervals at each dose level allow GI adaptation
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