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KPV Mechanism evidence comes from cell and animal studies
Age-dependent accumulation of dicarbonyls and advanced glycation endproducts (AGEs) associates with mitochondrial stress
Despite substantial advances, critical gaps remain in understanding how ABASnRK2 signaling interfaces with ABA-independent regulatory pathways and how epigenetic mechanisms including DNA methylation, histone modifications, and miRNA-mediated regulation shape drought adaptation across developmental stages and environmental contexts
This dual disruption prevents the effective clearance of lipid radicals (4, 19, 20)
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