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In a rat model of focal cerebral ischemia, 3-AB reduced lesion volumes and attenuated NMDA-induced neurotransmitter dysregulation 173

10.1038/s41392-024-01931-z Summary Keywords glucagon-like peptide-1 receptor, diabetes mellitus, -cell, insulin secretion, blood glucose Citation Li S, Huang N, Wang M, Huang W, Luo Y and Huang J (2025) GLP-1R in diabetes mellitus: from basic discovery to therapeutics development

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The GT activity was intensely reduced by 90% in response to DTNB compared to the control GT, ensuring the cysteine dependency of enzyme active sites