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9.7.1 Enhancement of incretin signaling glucagon-like peptide-1 and insulin sensitivity A primary mechanism by which probiotics exert glycemic control is the stimulation of glucagon-like peptide (GLP-1) secretion from enteroendocrine L-cells (435)

However, rare serious complications may occur in some patients receiving VPA chronically, including fatal haemorrhagic pancreatitis, bone marrow suppression, VPA-induced hepatotoxicity (VHT) and VPA-induced hyperammonaemic encephalopathy (VHE)