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This hormone sends signals to the brain that promote satiety, slow digestion, and reduce appetite

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For the master trial focusing on obesity or overweight, 2,339 eligible adults who had at least one weight-related comorbidity but without diabetes were randomised in a 1:1:1:1 ratio to receive retatrutide in doses of 4 mg, 9 mg, 12 mg, or a placebo

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