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Their effects on energy levels are indirect, mediated through improvements in metabolic parameters, weight reduction, and glycemic stability
Older adults also absorb levothyroxine less efficiently due to reduced gastric acid secretion and are more likely to be on PPIs, compounding the absorption issue
For individuals taking glucagon-like peptide-1 (GLP-1) receptor agonists such as semaglutide (Ozempic, Wegovy) and dulaglutide (Trulicity), or the dual GIP/GLP-1 receptor agonist tirzepatide (Mounjaro, Zepbound), maintaining adequate magnesium status may be particularly important
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