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When considering B12 injections, consult with a healthcare professional to discuss your individual needs, medical history, and potential risks associated with the treatment

By dosage, the mean changes were: 500 mcg: 127% 750 mcg: 176% (single study) 1,000 mcg: 280% 1,500 mcg: 310% 2000 mcg: 260% 5,000 mcg: 62% While 1,500 mcg of vitamin B12 showed the highest average increase, the effect plateaued or declined at higher doses, suggesting a possible saturation of absorption pathways

The other form, 5-deoxyadenosylcobalamin, is a cofactor needed by the enzyme that converts L-methylmalonyl-CoA to succinyl-CoA