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With careful dosage and monitoring, few of her patients need skin tightening or treatments for a gaunt facial appearance
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doi: 10.1161/jaha.116.003970 89 MiaoJ.LingA
The deacetylation of SHMT2 at K95 by SIRT3 (Wei et al., 2018) or desuccinylation at K280 by SIRT5 (Yang et al., 2018) has been shown to enhance the enzymatic activity of this protein, and the deacetylation by SIRT3 also has been shown to stabilize SHMT2 through avoiding its autophagic degradation (Wei et al., 2018)
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