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GLP-1 medications such as Semaglutide (Ozempic), Wegovy, Tirzepatide (Mounjaro), and Zepbound have become increasingly popular for weight loss and metabolic health

Food and Drug Administration (FDA) approved some GLP-1 medications, including semaglutide and liraglutide, for weight management in obese patients

The timing of bedtime is deliberate: GH secretion is most active during slow-wave sleep, and dosing sermorelin to coincide with that window is standard clinical practice to achieve the best response from the pituitary

Unlike immunosuppressive therapies, semaglutide does not increase infection risk through immune cell depletion, though any medication affecting gut permeability warrants careful monitoring