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In general, the current evidence does not fully meet the adjusted Bradford Hill Criteria
Alcohol interacts differently with each alternative
Acknowledgments This work was supported by the National Natural Science Foundation of China (grant 81670336) and the Wenzhou Grant for Scientific Talents (RX2016003), Wenzhou Science and Technology Bureau
Potential Side Effects and How to Handle Them It is common to feel some apprehension about side effects when starting a new medication
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