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Glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) are naturally occurring hormones that regulate appetite, insulin secretion, and metabolism
it appears to recapitulate the intracellular signals that exercise generates, including AMPK activation, mitochondrial biogenesis, and GLUT4 upregulation, in tissues that can no longer experience them through movement
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