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By constantly signaling to the brain that the body is full, peristalsis (rippling GI waves that push contents through the gut) is slowed, thereby disrupting the bodys natural digestion process. According to Fereday: The anecdotes of the early adopters are not necessarily that representative of how things will play out if this class of drugs goes mainstream

These medical interventions work synergistically with dietary optimization, exercise, sleep, and stress management to comprehensively address the metabolic dysfunction driving VLDL overproduction

This is what causes the "haggard" or "deflated" look

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