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others experience pronounced blood pressure changes, gastrointestinal side effects, and weight loss that temporarily render them ineligible for plasma donation

For flights, carry medication in carry-on luggage rather than checked baggage, where cargo hold temperatures may fall below freezing

Healthcare providers should engage patients in shared decision-making regarding treatment duration, establishing clear goals at treatment initiation and regularly reassessing the need for continued therapy

All available subjects in participating centres were initially included in the study and matching was subsequently performed retaining in the analyses only matched subjects