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While rare, its possible to have an allergic reaction, which could result in hives, swelling, or difficulty breathing
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The expression of IL-17A, Bax, caspase-3 and ROS, up-regulated the expression of p53, Bcl-2, Nrf2, HO-1, NQO-1, SOD (Li et al., 2020)
However many of these have off-target toxicity, low specificity, or are in early stages
Regular B12 supplementation can help prevent or treat deficiency symptoms such as fatigue, weakness, tingling or numbness in the extremities, memory issues, and anemia
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