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DSIP crosses the blood-brain barrier freely an unusual property for a peptide of its size via a non-competitive, non-saturable passive mechanism whose physicochemical determinants (lipophilicity, charge, molecular weight, and protein-binding) are now well characterised
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For chronic conditions, such as ongoing inflammation or gut issues, it may take a bit longertypically two to four weeksto see significant changes
Journal of Tissue Engineering
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