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Bottom Line on Effectiveness: For Maximum Weight Loss: Tirzepatide produces better results on average (7.6% more body weight lost) For Proven Long-Term Safety: Semaglutide has been on the market longer with more real-world data For Best Value: Compounded semaglutide at $199/month provides excellent results at lowest cost For Most People: Both medications are highly effective

Women of childbearing potential should notify their provider immediately if pregnancy is suspected, as tirzepatide should be discontinued when pregnancy is recognized

Storage Requirements Unreconstituted (lyophilized powder) BPC-157 maintains stability for 2 to 3 years at freezer temperatures or 1 to 2 years refrigerated

The Cochrane risk of bias (RoB2) tool was used to evaluate bias risks in the included studies