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Physician-guided programs can produce steady, sustained loss of 10 to 15 percent of body weight, and bariatric procedures typically go higher, depending on the patient and the procedure chosen

Healthy cognition: Limited research in healthy individuals suggests cognitive enhancement, though less evidence exists for this application than for neurological conditions

While effective, these drugs can be costly if not covered by insurance and often come with side effects

While more studies are needed, current evidence supports their potential to reduce CV risk through multiple direct and indirect mechanisms, offering hope for improved outcomes in a population with historically elevated premature mortality