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Kidney damage, typically resulting from dehydration caused by other side effects A potential risk of thyroid cancer animal studies have shown an increased risk for thyroid C-cell tumors, though that risk has not yet been confirmed in humans

Moreover, using the recognition of the conserved region Fc fragment and the neonatal Fc receptor (FcRn), IgG can escape lysosomal degradation after endocytosis with a half-life of 2 to 3 weeks through the FcRn-mediated recirculation mechanism