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When liver cells are damaged by alcohol, viral hepatitis, fatty liver disease or cirrhosis, stored B12 leaks into the bloodstream and the liver clears haptocorrin less efficiently

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In laboratory models, the compound has been associated with upregulation of the nitric oxide (NO) system, modulation of vascular endothelial growth factor receptor 2 (VEGFR2), and activation of focal adhesion kinase (FAK) pathways implicated in angiogenesis, cell migration, and tissue repair