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If a patient has a BMI of 27 or above , they'll usually need at least one weight-related condition, like high blood pressure, prediabetes, sleep apnea, or high cholesterol, to qualify
[32], activation of this pathway suppresses pro-inflammatory cytokine production via NF-B inhibition and promotes the synthesis of prostaglandin D2, which in turn further attenuates NF-B signaling and associated inflammatory cascades [40]
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