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Recent 2025 studies highlight their role in addressing metabolic slowdowns, particularly for those with B12 deficiencies that impair fat oxidation, potentially leading to higher body fat mass
Without adequate intake of B12, vegans can easily develop deficiency over time, leading to symptoms such as fatigue, weakness, constipation, loss of appetite, weight loss, and nerve problems therefore the researchers recommend that vegans and vegetarians should add vitamin B12 to their diet by eating fermented foods, particular types of mushroom that contain the vitamin and B12-enriched vegetables
That same rigidity affects chromatographic behavior, so laboratories verifying identity by HPLC should expect retention characteristics distinct from comparable-length linear peptides
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