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Evidence boundary The largest Phase 2b trial used oral dosing for 24 weeks and did not show statistically significant weight loss versus placebo
Fernndez-Salguero, University of Extremadura, Spain Reviewed by Qiulun Lu, Nanjing Medical University, China
Zero adverse events across all groups No adverse events were reported in any of the three groups over the full 6-month treatment period
They are typically transient and do not require stopping the protocol
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