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For patients who are not candidates for GLP-1 therapy or who have tried it without success, bupropion-naltrexone is an FDA-approved alternative with a reasonable evidence base
We observed no detectable colocalization of GADD45A with glial cell markers, including IBA1 (microglia), GFAP (astrocytes), and MBP (oligodendrocytes) (Fig
The abdomen also has the lowest pain scores in patient surveys
Depression never really made me sad, but it made me deeply unmotivated and emotionally numb
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