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Vitamin B 12 deficiency can develop for the following reasons: Absence of intrinsic factor, also called pernicious anemia: Intrinsic factor is a protein secreted by cells of the stomach lining
In addition, some putative effects of GLP-1RAs on cognitive and mental health symptoms may not require direct activity in the CNS, but rather be mediated by the actions that these medications express in the periphery across immune, endocrinemetabolic and gutbrain axis mechanisms (Fig
Science 362:eaat9528
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