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The between-group interaction for unstable angina in subjects with prior MI or stroke compared with no prior MI or stroke was significant (p = 0.02 for interaction), with a significant reduction in hospitalization for unstable angina for semaglutide vs placebo in subjects with no prior MI or stroke (p = 0.03)
At 8mg, the glucagon receptor stimulation is strong enough to produce the tingling and altered skin sensitivity reported in trials
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